Actinomycetes, 1997, Vol.8, Parts 1 and 2. pp. 1-9
Structure elucidation of the antibiotic demalonylniphimycin by
two-dimensional NMR techniques
V. IVANOVA & R. SCHLEGEL
Code Number: AC97001
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ABSTRACT.
The structure of the antibiotic demalonylniphimycin has been determined by
two-dimensional NMR techniques. Mass spectroscopy indicated a MH^+ of 1056.
The molecular formula was determined as C56H101N3O15 (MW. 1055). All other
structural information was obtained from ^1H and ^13C NMR, ^1H - ^1H
double-quantum filtert, phase sensitive COSY experiments, while the
correlation between proton and carbon chemical shifts was performed by the
^1H - ^13C COSY experiment. Demalonylniphimycin is active against Gram-
positive bacteria and fungi.
Copyright 1997 C.E.T.A., The International Centre for Theoretical and
Applied Ecology, Gorizia
