The use of magnesium sulphate for the treatment of severe pre-eclampsia and eclampsia

Background : Pre-eclampsia and eclampsia are important causes of maternal and perinatal morbidity and mortality in the developing countries. There is need to provide the most effective management to pre-eclamptic and eclamptic patients. There is now evidence that magnesium sulphate is the most effective anticonvulsant.
Method : In this article, a literature review was made on the contribution of pre-eclampsia and eclampsia to maternal mortality and how it can be curtailed by the use of magnesium sulphate.
Results : The drug is administered by the Pritchard or Zuspan regimen, although modifications in the two protocols have been reported.
Conclusion : A Nigerian national protocol has been developed on its use. There is need for further training of health workers on how to use this important drug.