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Australasian Biotechnology (backfiles)
ISSN: 1036-7128
Vol. 6, No. 4, 1996
Bioline Code: au96009
Full paper language: English
Document type: Research Article
Document available free of charge

Australasian Biotechnology (backfiles), Vol. 6, No. 4, 1996

 en Production of therapeutic proteins in yeasts: A review


Australasian Biotechnology, 
Volume 6 Number 4, July/August 1996,pp.230-237

Production of therapeutic proteins in yeasts: A review 

Prasad Rallabhandi and Pak-Lam Yu, 

Code Number: AU96009
Size of Files:
    Text: 40.4K
    Graphics: No associated graphics files

This paper reviews the use of yeasts in the production of
heterologous proteins with a special focus on therapeutic
proteins. Yeast offers a number of advantages as an expression
system over prokaryotic systems. Yeasts are eukaryotic in
nature with consequent associated cellular processes such as
protein secretion and post-translational modification of
proteins to render the recombinant proteins biologically
active. This is essential for the naturally secreted
therapeutic proteins. With the combination of recombinant
techniques and fermentation technology, it is possible to
explore yeasts as hosts for the expression and secretion of
medically important proteins. 

Copyright 1996 Australian Biotechnology Association Ltd.


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