Australasian Biotechnology,
Volume 8 Number 2, March/April 1998, pp. 86-90
Special Feature
Vaccine Biotechnology
Code Number:AU98016
Sizes of Files:
Text: 22K
Graphics: Photograph (jpg) - 59K
Our Special Feature for this issue highlights developments
in Vaccine
Biotechnology.
Bacterial Vectors: why have they failed to deliver
?
Richard Strugnell, Cameron Simmons, Odilia Wijburg, Tania
Uren, Damien
Drew and
Sarah Dunstan,
Bacterial vaccine vectors have been studied experimentally
for over twenty years
yet there are
no vector-based vaccines in commercial human or veterinary use
today. The absence of
human vector-based vaccines is probably due to problems
associated with testing human
vaccines, and a lack of funds to support vaccines for use in
developing countries.
Vector-based veterinary vaccines are currently not competitive
with combination adjuvanted
vaccines but may have a niche under certain circumstances. The
future of vaccine vectors
may lie in the delivery of DNA vaccines.
Copyright 1998 Australian Biotechnology Association Ltd.
