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Effect of different concentrations of hr-EGF on the healing of a full thickness-skin wound in rats Berlanga, Jorge; Perez, Luis C.; Moreira, E.; Orrego, A.; Boix, E.; Gonzalez, Tania & Lopez-Saura, Pedro Abstract Recent evidence suggest that wound healing is regulated by peptide growth factors through autocrine and paracrine mechanisms. By the results presented here, improvement of the healing process whether in Epidermis or in Dermis, might be elicited by the presence of a limited range of EGF concentrations, what seems to depend upon specific cell sensitivity to EGF.

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