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Biotecnologia Aplicada
Elfos Scientiae
ISSN: 0684-4551
Vol. 13, No. 3, 1996, pp. 167-180
Bioline Code: ba96073
Full paper language: English
Document type: Research Article
Document available free of charge

Biotecnologia Aplicada, Vol. 13, No. 3, 1996, pp. 167-180

 es
Kamerling, Johannis P.

Resumen

El establecimiento de los patrones de glicosidacion de farmacos basados en glicoproteinas humanas recombinantes constituye un elemento de gran actualidad en las tendencias modernas de desarrollo de esas biomoleculas. El presente trabajo de revision pasa revista al estado del arte del analisis de glicanos de las glicoproteinas. Ademas, sumariza en mayor detalle la glicosidacion de los activadores del plasminogeno y las eritropoietinas.

Palabras-clave
glicoproteinas recombinantes, analisis de carbohidratos, activador de plasminogeno, eritropoietina

 
 en Carbohydrate features of recombinant human glycoproteins
Kamerling, Johannis P.

Abstract

In the present approaches of developing pharmaceutically relevant drugs based on recombinant human glycoproteins, the establishment of the glycosylation patterns of these biomolecules is highly actual. In this minireview a short overview of the state of the art with respect to glycoprotein glycan analysis is given. Furthermore, the glycosylation of plasminogen activators and erythropoietins is summarized in more detail.

Keywords
recombinant glycoproteins, carbohydrate analysis, plasminogen activator, erythropoietin

 
© Copyright 1996 Elfos Scientiae
Alternative site location: http://elfosscientiae.cigb.edu.cu/Archivo.asp?Id=6

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