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Biokemistri
Nigerian Society for Experimental Biology
ISSN: 0795-8080
Vol. 15, No. 1, 2003, pp. 7-15
Bioline Code: bk03014
Full paper language: English
Document type: Research Article
Document available free of charge

Biokemistri, Vol. 15, No. 1, 2003, pp. 7-15

 en Effect Of Aqueous Extract Of Canavalia Ensiformis check for this species in other resources Seeds On Hyperlipidaemia And Hyperketonaemia In Alloxan-induced Diabetic Rats
Nimenibo-Uadia, Rachel

Abstract

The effect of Canavalia ensiformis check for this species in other resources (DC) seeds on diabetic albino rats was studied. Alloxan-induced diabetes mellitus was accompanied by several fold increases in plasma glucose and urinary excretion of glucose. Total plasma triacylglycerol, cholesterol and β-hydroxybutyrate were also significantly increased (p<0.05). One-week oral administration of an aqueous extract of the seeds of C. ensiformis significantly reduced (p<0.05) hyperlipidaemia and hyperketonaemia in the diabetic rats. These results suggest that C. ensiformis seeds possess an antidiabetic principle and can be useful for the treatment of diabetes mellitus.

Keywords
Canavalia ensiformis, alloxan, diabetes mellitus, triacylglycerol, cholesterol, β-hydroxybutyrate

 
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