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Biokemistri
Nigerian Society for Experimental Biology
ISSN: 0795-8080
Vol. 15, No. 1, 2003, pp. 22-26
Bioline Code: bk03016
Full paper language: English
Document type: Research Article
Document available free of charge

Biokemistri, Vol. 15, No. 1, 2003, pp. 22-26

 en Changes In Levels Of Serum Beta-carotene, Vitamin A And Cholesterol In Breast Cancer Of Pre And Post Menopausal Nigerian Women
Olabinri, Babtunde M.; Odetola, Adetoun A. & Adebamowo, Clement A.

Abstract

Twenty newly diagnosed breast cancer patients were assessed for serum vitamin A, β-carotene and total cholesterol levels with their matched control (n = 20). The mean age and standard deviation of pre-menopausal breast cancer patients was 34.75± 6.57 while the mean age and standard deviation for controls was 32.00 ±8.79 years. There was no statistical difference in age between the two groups (P< 0.05). There was evidence of decrease in the mean serum vitamin A with increasing stage of advanced breast cancer. However, the mean serum β-carotene level showed significant decrease in trend with increasing stage of advanced breast cancer (P< 0.05). Serum total cholesterol was negatively correlated with serum vitamin A but was found to be positively correlated though non-significantly with serum β-carotene in breast cancer patients and control (r = 0.10, p> 0.95 for cases; r = 0.05, p> 0.05 for control).

Keywords
β-carotene, vitamin A, breast cancer, menopause

 
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