Nigerian Society for Experimental Biology
Vol. 16, No. 1, 2004, pp. 23-27
Bioline Code: bk04004
Full paper language: English
Document type: Research Article
Document available free of charge
Biokemistri, Vol. 16, No. 1, 2004, pp. 23-27
© Copyright 2004 - Nigerian Society for Experimental Biology
Metal Binding Acute Phase Proteins And Trace Elements In Nigerian Children With Urinary Schistosomiasis|
Arinola, Olatunbosun G.
Fifty-five Nigerian children with urinary schistosomiasis (USS) and 34
apparently healthy children of matched ages and sexes were considered for
this study. In these children, metal binding acute phase proteins (transferrin
and caeruloplasmin) and trace elements were measured by single radial immunodiffusion
and atomic absorption spectrophotometry respectively. The result shows
that Cd, Mn, albumin and transferrin were reduced (p<0.01, p>0.20,
p<0.01 and p<0.01 respectively) while Fe, Cu and caeruloplasmin were
raised (p<0.01, p<0.01 and p<0.01 respectively) in USS subjects
when compared with the controls. Low levels of transferrin might be responsible
for raised level of plasma Fe, which is in turn modulated by caeruloplasmin.
It may be concluded that trace elements and antioxidants are involved in
the pathogenesis of USS.
Schistosomiasis, elements, proteins, antioxidants, children