search
for
 About Bioline  All Journals  Testimonials  Membership  News  Donations


Biokemistri
Nigerian Society for Experimental Biology
ISSN: 0795-8080
Vol. 17, No. 2, 2005, pp. 149-156
Bioline Code: bk05021
Full paper language: English
Document type: Research Article
Document available free of charge

Biokemistri, Vol. 17, No. 2, 2005, pp. 149-156

 en Comparative Study Of The Hypoglycemic And Biochemical Effects Of Catharanthus Roseus check for this species in other resources (Linn) G. Apocynaceae (Madagascar Periwinkle) And Chlorpropamide (Diabenese) On Alloxan-induced Diabetic Rats
Iweala, Emeka E. J. & Okeke, Clement U.

Abstract

The effect of the aqueous extracts of Catharanthus roseus check for this species in other resources and chlorpropamide (Diabenese) on the levels of serum cholesterol, total protein, lipid peroxidation, blood glucose and liver enzymes were compared in alloxan-induced diabetic rats. Four groups namely A, B, C and D comprising of nine rats each were used. A and B were administered with chlorpropamide and C. roseus extracts respectively, while C and D served as diabetic and non-diabetic controls respectively. The results showed comparatively significant reductions (P≤ 0.05) in the levels of glucose, protein, cholesterol, lipid peroxidation and liver enzymes in the groups administered C. roseus extracts and chlorpropamide relative to the controls. The reductions were higher in the groups treated with C. roseus extract than in the groups treated with diabenese.

Keywords
Catharanthus roseus, Diabenese, alloxan-induced diabetes

 
© Copyright 2005 - Nigerian Society for Experimental Biology

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2017, Site last up-dated on 05-Dec-2017.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil