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Biokemistri
Nigerian Society for Experimental Biology
ISSN: 0795-8080
Vol. 18, No. 2, 2006, pp. 77-81
Bioline Code: bk06012
Full paper language: English
Document type: Research Article
Document available free of charge

Biokemistri, Vol. 18, No. 2, 2006, pp. 77-81

 en Antioxidant Activity Of The Exudate From Aloe Barbadensis check for this species in other resources Leaves In Diabetic Rats
Nwanjo, Harrison U.

Abstract

The effects of the exudate of Aloe barbadensis check for this species in other resources leaves on oxidative stress and some antioxidant status of streptozotocin induced - diabetic rats were studied. There was significant reduction in scavenging enzymes like superoxide dismutase (SOD) activity and significant increase in signs of oxidative tissue damage, such as lipid peroxidation products (plasma MDA) in streptozotocin induced - diabetic rats. Treatment with Aloe barbadensis (150mg/kg) increased antioxidant enzymes like SOD activities and significantly reduced lipid peroxidation products. This study shows that high blood sugar leads to increased oxidative stress and that exudates of Aloe barbadensis leaves possessed antioxidant activity as shown by increased scavenging SOD activity and decreases in lipid peroxidation products levels.

Keywords
Diabetes, Aloe barbadensis, oxidative stress, Antioxidant enzymes

 
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