search
for
 About Bioline  All Journals  Testimonials  Membership  News  Donations


Biokemistri
Nigerian Society for Experimental Biology
ISSN: 0795-8080
Vol. 21, No. 2, 2009, pp. 59-65
Bioline Code: bk09008
Full paper language: English
Document type: Research Article
Document available free of charge

Biokemistri, Vol. 21, No. 2, 2009, pp. 59-65

 en Comparative Effects of the Leaves of Gongronema latifolium check for this species in other resources and Vernonia amygdalina check for this species in other resources Incorporated Diets on the Lipid Profiles of Rats
Ugwu, Chidiebere E.; Alumana, Edwin O. & Ezeanyika, Lawrence U.S.

Abstract

The hypolipidaemic effects of the leaves of Gongronema latifolium check for this species in other resources (GL) and Vernonia amygdalina check for this species in other resources (VA)diet preparations on the lipid profile of rats were compared. The rats were fed for 28 days on diet specially formulated to contain 5%, 15% and 30% by weight of the leaves of each plant respectively while the control group was fed standard rat diet. The serum total cholesterol (TC), triacylglycerol (TG), high-density lipoprotein cholesterol (HDL-C) and low- density lipoprotein cholesterol (LDL-C) were determined on blood samples collected on the 28th day. The results show that the VA diet induced a significantly lower serum total cholesterol level at the 15% and 30% concentrations relative to the GL diet preparation. The results also show that there was no significant difference between the effects of GL and VA diet preparations at the various levels of treatments. The comparison of the effects of the two diet preparations show that VA produced higher levels of HDL-C compared to GL which was significant at 5% and 15% concentrations respectively. It appears from our results that VA diet preparation may have better hyperlipidaemic effect than GL diet preparation. Therefore, VA may have better therapeutic promise in preventing lipid related pathologies compared to GL

Keywords
Gongrnema latifolium, Vernonia amygdalina, lipid profile

 
© Copyright © 2009 Nigerian Society for Experimental Biology

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2017, Site last up-dated on 05-Dec-2017.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil