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Nigerian Society for Experimental Biology
ISSN: 0795-8080
Vol. 21, No. 2, 2009, pp. 95-99
Bioline Code: bk09013
Full paper language: English
Document type: Research Article
Document available free of charge

Biokemistri, Vol. 21, No. 2, 2009, pp. 95-99

 en Alteration of Plasma Lipid Profile and Atherogenic Indices of Cholesterol Loaded Rats by Tridax procumbens check for this species in other resources Linn: Implications for the Management of Obesity and Cardiovascular Diseases
Ikewuchi, Chigozie Jude & Ikewuchi, Chidinma Catherine


The effect of the administration of 20mg/100g aqueous extract of the leaves of Tridax procumbens check for this species in other resources on the packed cell volume (PCV), daily weight gain, plasma lipid profiles and atherogenic indices of rats fed 1g/100g cholesterol, was investigated. The mean daily weight gain and plasma concentrations of triglyceride, LDL-, VLDL- and total cholesterol, as well as the atherogenic indices [Cardiac Risk Ratio (CRR), Atherogenic Coefficient (AC) and Atherogenic Index of Plasma (AIP)] of the treated animals were all significantly lower (p<0.05) than those of the test control and control. The PCV and plasma HDL-cholesterol level of the treated animals was significantly higher (p<0.05) than that of the test control, although lower than that of the control. These results suggest a possible protective role of the extract against the development of cardiovascular diseases, as well as dyslipidemic conditions, whether primary or secondary to diabetes mellitus, hypertension and obesity

Hypertension, hypocholesterolemia, lipid profile, obesity, Tridax procumbens

© Copyright © 2009 Nigerian Society for Experimental Biology

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