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Biokemistri
Nigerian Society for Experimental Biology
ISSN: 0795-8080
Vol. 24, No. 1, 2012, pp. 48-51
Bioline Code: bk12006
Full paper language: English
Document type: Research Article
Document available free of charge

Biokemistri, Vol. 24, No. 1, 2012, pp. 48-51

 en In vitro assay of potential antifungal and antibacterial activities of extracts of Borassus aethiopum check for this species in other resources Mart
Sakandé, J.; Nikiéma, A.; Kabré, E.; Lompo, M.; Nikiema, J.B.; Nacoulma, O.G.; Sawadogo, M. & Guissou, I.P.

Abstract

The anti-inflammatory, antipyretic, and pro-apoptotic properties of extracts of Borassus aethiopum check for this species in other resources have been reported in the literature. In this study, we investigated the antifungal and antibacterial properties of Borassus aethiopum male inflorescences extracts. The antifungal and antibacterial activity was studied by agar well diffusion method in vitro. The effect of antibacterial potential was examined against Gram positive bacteria ( Staphylococcus aureus check for this species in other resources ), and Gram negative bacteria i.e., ( Escherichia coli check for this species in other resources and Enterobacter cloacae check for this species in other resources ). In the antifungal activity assays, the dermatophytes strains Trichophyton rubrum check for this species in other resources , Trichophyton interdigitale check for this species in other resources , Trichophyton soudanense check for this species in other resources , Microsporum langeronii check for this species in other resources , and Epidermophyton floccosum check for this species in other resources were used. The E2F2 extract showed strong inhibitory activity on four of the five fungal species used against ketoconazole, a standard antifungal drug. However, the E2F2 extract displayed weak antibacterial activity against the bacterial strains tested. The results of the present study support the ethnomedicinal uses of Borassus aethiopum for the treatment of fungal diseases. The phytochemical screening of E2F2 extract revealed the presence of sterols, triterpenes and saponins, witch may be involved in the antifungal activity.

Keywords
Antifungal, antibacterial, Borassus aethiopum

 
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