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Biokemistri
Nigerian Society for Experimental Biology
ISSN: 0795-8080
Vol. 24, No. 2, 2012, pp. 77-81
Bioline Code: bk12012
Full paper language: English
Document type: Research Article
Document available free of charge

Biokemistri, Vol. 24, No. 2, 2012, pp. 77-81

 en Renal function status of Nigerian patients infected with Hepatitis B virus
Ayelagbe, Olubunmi G. & Oladipo, Tunde S.

Abstract

In Hepatitis B virus (HBV) infection is an important cause of morbidity and mortality in liver disease and hepatocellular carcinoma. It has also been implicated in a variety of renal diseases. This relationship was investigated in hepatitis B virus patients in Nigeria where the infection is highly endemic. Fifty hepatitis B positive patients (aged 27.3 ± 7.5 years) and 50 control subjects (aged 25.1 ± 3.6 years) were recruited in this study. Random blood sample was drawn from all subjects. Serum electrolyte, urea and creatinine were measured using standard laboratory methods. Serum potassium concentration was higher (5.16 ± 2.30, p <0.05) in hepatitis B carriers compared to controls (4.25 ±0.5). There was an inverse correlation between bicarbonate and chloride (r = -0.67, p <0.01) in HBV patients. Results from this study showed a possible relationship between hepatitis B infection and insufficient renal function.

Keywords
Hepatitis B virus, renal disease, electrolytes

 
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