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Biokemistri
Nigerian Society for Experimental Biology
ISSN: 0795-8080
Vol. 26, No. 3, 2014, pp. 85-87
Bioline Code: bk14014
Full paper language: English
Document type: Short Communication
Document available free of charge

Biokemistri, Vol. 26, No. 3, 2014, pp. 85-87

 en Aqueous extracts of African mistletoe (Loranthus bengwensis) leaves exert hypoglycaemic effects in normal rabbits
Osadolor, Humphry B. & Ojewe, David D.

Abstract

The hypoglycaemic effect of aqueous extract of the leaves of African mistletoe (Loranthus bengwensis) growing on Kola nuts plants (Kola acuminate) was studied on normal rabbits. The results obtained showed that administration of 100 mg/kg aqueous extract of the plant for 21 days elicited a 49% decrease in plasma glucose, while a dose of 200 mg/kg led to a decrease of 45%. In comparison, treatment with 0.1 mg/Kg Daonil caused a 72% reduction in plasma glucose concentration. This preliminary finding provides a basis for further investigation into the mechanism through which the plant extract exerts its hypoglycaemic effect and its potential use in the management of diabetes mellitus.

Keywords
Hypoglycaemia; plasma glucose; mistletoe; diabetes; rabbits

 
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