Indian Journal of Critical Care Medicine
Medknow Publications on behalf of the Indian Society of Critical Care Medicine
Vol. 9, No. 3, 2005, pp. 133-136
Bioline Code: cm05020
Full paper language: English
Document type: Research Article
Document available free of charge
Indian Journal of Critical Care Medicine, Vol. 9, No. 3, 2005, pp. 133-136
© Copyright 2005 Indian Journal of Critical Care Medicine.
Methylprednisolone as adjuvant in treatment of acute respiratory distress syndrome owing to leptospirosis-a pilot study|
Ittyachen Abraham, Lakshmanakumar VK, Eapen CK, Joseph MR
Background: Acute respiratory distress syndrome (ARDS) owing to leptospirosis is associated with a high mortality. This is in spite of mechanical ventilation in a critical care setting. ARDS by its very nature, associated with economic constraints in our patients has made treating these patients a challenge.
Objective: To study if combination of methylprednisolone and noninvasive ventilation is life-saving in ARDS owing to leptospirosis.
Design: Interventional pilot study.
Setting: Medical intensive care unit of a rural medical college hospital.
Participants: Eight patients diagnosed to have ARDS owing to leptospirosis.
Main outcome indicator: Survival.
Results: Seven out of eight patients who were treated with methylprednisolone and noninvasive ventilation recovered fully to resume normal life.
Conclusion: Methylprednisolone with noninvasive ventilation is life-saving in ARDS owing to leptospirosis.
ARDS, Leptospirosis, Methylprednisolone, Noninvasive ventilation
Alternative site location: http://www.ijccm.org/