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Indian Journal of Critical Care Medicine
Medknow Publications on behalf of the Indian Society of Critical Care Medicine
ISSN: 0972-5229
EISSN: 1998-359x
Vol. 10, No. 2, 2006, pp. 112-114
Bioline Code: cm06017
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Critical Care Medicine, Vol. 10, No. 2, 2006, pp. 112-114

 en Case Report - Hemophagocytosis and miliary tuberculosis in a patient in the intensive care unit
Khan FahmiYousef, Fawzy Zeinab, Siddiqui Issar, Yassin MohamedA


We report a 60-year-old woman who was admitted to our hospital with high-grade fever and dyspnea. Laboratory findings showed pancytopenia and examination of aspirated bone marrow showed mature histiocytes with marked hemophagocytosis. The patient's condition continued to deteriorate despite adequate antibiotic coverage. Her respiratory condition worsened, so she was transferred to the ICU and ventilated. Transbroncheal biopsy was performed, which showed caseating granuloma suggesting pulmonary TB. Eight weeks later, bone marrow culture in Lowenstein media confirmed the presence of mycobacterium tuberculosis susceptible to INH, Rifampcine, pyrasinamide, ethambutol and streptomycin. Though anti-tuberculous therapy was started, she died after 28 days of hospitalization.

Hemophagocytosis, critically ill patient, miliary tuberculosis

© Copyright 2006 Indian Journal of Critical Care Medicine.
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