Indian Journal of Critical Care Medicine
Medknow Publications on behalf of the Indian Society of Critical Care Medicine
Vol. 14, No. 3, 2010, pp. 109-112
Bioline Code: cm10024
Full paper language: English
Document type: Research Article
Document available free of charge
Indian Journal of Critical Care Medicine, Vol. 14, No. 3, 2010, pp. 109-112
© Copyright 2010 Indian Journal of Critical Care Medicine.
A case control study of cardiovascular health in chemical war disabled Iranian victims|
Rohani, Atoosheh; Akbari, Vahid & Moghadam, Fatemeh Tabesh
Background: Sulfur mustard (SM) is an alkylating chemical warfare agent that was widely used during Iran-Iraq war between 1983 and 1988. SM exposure leads to various late complications. The aim of this study was to determine the late cardiovascular effects of SM in war-disabled Iranian victims.
Materials and Methods: This was a retrospective cohort case control study on 50 patients with symptoms of SM exposure and 50 cases who had been in Iran-Iraq war, without chemical injury. We performed exercise stress test and echocardiography for all of patients.
Results: The study group comprised 100 males of mean age 45.6 ± 6.2 years. In chemical war injury group, two patients (4%) had positive exercise stress test. On coronary angiography, they were found to have coronary artery disease. One patient had severe mitral regurgitation and normal coronary angiography; he was referred for mitral valve replacement. Left ventricular (LV) diastolic abnormality was detected in 23% of these subjects. In another group, 5% had LV diastolic abnormality (P = 0.02) and all of them had normal stress test.
Conclusions: Cardiovascular abnormalities are another late complication in chemical war disabled Iranian victims. Diastolic dysfunction was the most common abnormality in both groups of patients.
Cardiovascular abnormalities, chemical warfare, mustard gas
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