Indian Journal of Critical Care Medicine
Medknow Publications on behalf of the Indian Society of Critical Care Medicine
Vol. 15, No. 4, 2011, pp. 230-232
Bioline Code: cm11063
Full paper language: English
Document type: Case Report
Document available free of charge
Indian Journal of Critical Care Medicine, Vol. 15, No. 4, 2011, pp. 230-232
© Copyright 2011 Indian Journal of Critical Care Medicine.
Anti-thymocyte globulin induced non-cardiogenic pulmonary edema during renal transplantation|
Parikh, Beena K.; Bhosale, Guruprasad P. & Shah, Veena R.
Non-cardiogenic pulmonary edema (NCPE) is a clinical syndrome characterized by simultaneous presence of severe hypoxemia, bilateral alveolar infiltrates on chest radiograph, without evidence of left atrial hypertension/congestive heart failure/fluid overload. The diagnosis of drugrelated NCPE relies upon documented exclusion of other causes of NCPE like gastric aspiration, sepsis, trauma, negative pressure pulmonary edema. We describe a 28year-old, 50 kg male with ASA risk III posted for laparoscopic renal transplantation, who developed NCPE after 4 hours of administration of rabbit anti-human thymocyte immunoglobulin (ATG). He was successfully treated with mechanical ventilatory support and adjuvant therapy. This report emphasizes that this fatal complication may occur with use of ATG.
Anti-human thymocyte immunoglobulin, non-cardiogenic pulmonary edema, renal transplantation
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