Indian Journal of Cancer
Medknow Publications on behalf of Indian Cancer Society
Vol. 41, No. 1, 2004, pp. 41-46
Bioline Code: cn04008
Full paper language: English
Document type: Research Article
Document available free of charge
Indian Journal of Cancer, Vol. 41, No. 1, 2004, pp. 41-46
© Copyright 2004 - Indian Journal Cancer.
Case Report - Gangliogliomas: A Report of Five Cases|
Nair V, Suri VS, Tatke M, Saran RK, Malhotra V, Singh D
Gangliogliomas are rare tumors of the Central Nervous System. Five Gangliogliomas were diagnosed out of 1560 brain tumours surgically resected out in a period of 5years accounting for 0. 32%. We have tried to discuss in detail the pathological features of these tumours and have mentioned the clinical and radiological features associated with them. All the slides, tissue blocks and pathology reports of the surgical specimens of gangliglioma were reviewed and the clinical and radiological data reviewed. The ages of the patients ranged from 7 - 65 years with 4 males and 1 female. The tumors were located in the lateral ventricle (a rare site), temporal, parietal and the frontal lobes with duration of seizures varying from 1-9 years. The tumors were diagnosed by the presence of a dual population of neoplastic ganglionic and glial components. The glial components consisted of pilocytic astrocytes (l case), fibrillary astrocytes (2 cases), oligodendrocytes (1 case) and anaplastic astrocytes and oligodendrocytes (1 case). There was one-grade I GG, three-Grade II GGs and one-grade III GG. Astrocytes were the commonest glial component of GGs, either pilocytic or fibrillary. Oligodendrocytes as the glial component of GGs was seen in 2 cases one of which was anaplastic and this is a rare finding.
Ganglioglioma, Anaplastic Gangliogliomas.
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