search
for
 About Bioline  All Journals  Testimonials  Membership  News  Donations


Indian Journal of Cancer
Medknow Publications on behalf of Indian Cancer Society
ISSN: 0019-509X
EISSN: 1998-4774
Vol. 44, No. 1, 2007, pp. 12-16
Bioline Code: cn07003
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Cancer, Vol. 44, No. 1, 2007, pp. 12-16

 en Role of radionuclide scintigraphy in the detection of parathyroid adenoma
Singh N, Krishna BA

Abstract

Background: Preoperative detection of parathyroid adenoma is a diagnostic challenge. The sonography and computerized tomography (CT) scan demonstrate high sensitivity but low specificity. The advent of radionuclide scanning technique has enhanced the specificity in this context.
Aim: We undertook a study to assess the role of radionuclide scanning in suspected cases of parathyroid adenomas.
Materials And Methods: Totally 28 cases were incorporated in the study. The suspicion was raised either due to raised PTH levels or recurrent calcinosis. Most of these patients had estimation of calcium done as a routine or specific investigation. The parathyroid scan was performed using either of the two techniques - Dual isotope subtraction or Sestamibi washout technique. We also used the recent approach of fusion imaging (CT + tomographic nuclear images) in selected cases.
Results: There were 16 true positive, 10 true negative, 1 false negative and 1 equivocal scan findings. The findings were compared with sonography, CT Scan and PTH values. The true positive yield in our study was 57%, true negative 35% and the overall sensitivity and specificity was found to be 94% and 100% respectively.
Conclusion: We conclude that parathyroid scintigraphy is a reliable and sensitive technique in the preoperative detection of parathyroid adenomas and should be the first choice of imaging modality in suspicion of parathyroid adenoma.

Keywords
Highest sensitivity and specificity, parathyroid adenoma, preoperative detection, radionuclide scintigraphy

 
© Copyright 2007 Indian Journal of Cancer.
Alternative site location: http://www.indianjcancer.com/

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2022, Site last up-dated on 10-Dec-2021.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Internet Data Center of Rede Nacional de Ensino e Pesquisa, RNP, Brazil