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Indian Journal of Cancer
Medknow Publications on behalf of Indian Cancer Society
ISSN: 0019-509X
EISSN: 1998-4774
Vol. 44, No. 3, 2007, pp. 115-118
Bioline Code: cn07020
Full paper language: English
Document type: Case Report
Document available free of charge

Indian Journal of Cancer, Vol. 44, No. 3, 2007, pp. 115-118

 en 18F-FDG uptakes in leptomeningeal metastases from carcinoma of the breast on a positron emission tomography/computerized tomography study
Shah, S.; Rangarajan, V.; Purandare, N.; Luthra, K. & Medhi, S.


Leptomeningeal metastases (LM) are most commonly observed in hematological malignancies. With prolonged survival in solid tumors, an increased frequency of metastases is noted in these tumors too. Early diagnosis, when the patient has minimal neurological disability, is associated with prolonged survival and improved functional outcome although the therapy is palliative. The diagnosis of LM is difficult, and the demonstration of tumor cells in the cerebrospinal fluid remains the gold standard. This can also be done by definitive neuroimaging. MRI is routinely used in this aspect. We discuss here a case where 18F-FDG PET/CT (Fluoro-de-oxy glucose positron emission tomography/computerized tomography) study helped us in the diagnosis of LM. Whole-body PET/CT imaging could be a useful tool in identifying the possibility of metastases of breast carcinoma in the usual sites and the not-so-usual sites of metastases.

Breast carcinoma, FDG, leptomeningeal metastases, positron emission tomography/computerized tomography

© Copyright 2007 Indian Journal of Cancer.
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