Indian Journal of Cancer
Medknow Publications on behalf of Indian Cancer Society
Vol. 46, No. 1, 2009, pp. 34-39
Bioline Code: cn09006
Full paper language: English
Document type: Research Article
Document available free of charge
Indian Journal of Cancer, Vol. 46, No. 1, 2009, pp. 34-39
© Copyright 2009 Indian Journal of Cancer.
Desmoid tumors: Experience of 32 cases and review of the literature|
Kumar, V.; Khanna, S.; Khanna, A.K. & Khanna, R.
Background: Desmoids are infiltrative, locally destructive, soft tissue tumors. Although they do not metastasize, the incidence of local recurrence is quite high. Aim : Present study aimed at reporting the 10-year experience of 32 desmoid cases and reviewing some facts with symptoms, investigation, and treatment of the disease.
Materials and Methods : Thirty two cases of desmoid tumors were reviewed over a 10-year span. Surgical resection and adjuvant radiotherapy were the treatments of choice whenever histological margins were positive.
Results : Multiparous women in reproductive age were the most commonly afflicted. The commonest site of presentation was the abdominal wall. Ninety one percent (20/22) were infraumbilical. The tumors were found in the rectus sheath in 14 patients (64%) and were laterally situated in 8 patients (36%). Local infiltration was found in six patients and the urinary bladder was most commonly involved (3/6). Locally recurrent desmoids were seen in eight patients (25%).
Conclusions : In our experience, 25% of the desmoid tumors (8/32) were recurrent and postoperative radiotherapy did not seem to influence the local recurrence rate. The most important predictor for recurrence was tumors of> 5 cm.
Desmoid tumors, radiotherapy, recurrence, surgery
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