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Indian Journal of Cancer
Medknow Publications on behalf of Indian Cancer Society
ISSN: 0019-509X
EISSN: 1998-4774
Vol. 46, No. 2, 2009, pp. 108-119
Bioline Code: cn09023
Full paper language: English
Document type: Symposium
Document available free of charge

Indian Journal of Cancer, Vol. 46, No. 2, 2009, pp. 108-119

 en Current Concepts in the Pathology and Genetics of Gliomas
Sarkar, C.; Jain, A. & Suri, V.

Abstract

In recent years, there has been a marked improvement in our understanding of molecular genetics of gliomas. These advancements offer hope for development of tailored therapies targeting a tumor′s unique molecular profile, and may also translate into improved classification and identification of newer prognostic markers. This review focuses on the neuropathological features of different types of glial neoplasms according to the World Health Organization classification, and the recent advances in their molecular biology with emphasis on the genetic mechanisms underlying tumor progression, diagnostic and prognostic markers and potential therapeutic targets.

Keywords
Glioma, oligodendroglioma, astrocytoma, glioblastoma, 1p/19q deletion

 
© Copyright 2009 Indian Journal of Cancer.
Alternative site location: http://www.indianjcancer.com/

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