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Indian Journal of Cancer
Medknow Publications on behalf of Indian Cancer Society
ISSN: 0019-509X
EISSN: 1998-4774
Vol. 47, No. 4, 2010, pp. 400-405
Bioline Code: cn10097
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Cancer, Vol. 47, No. 4, 2010, pp. 400-405

 en Resection and reconstruction of mediastinal great vessels in invasive thymoma
Arvind, K.; Roman, D.; Umashankkar, K.; Pramod, K. J.; Shiv, K. C. & Neeti, M.

Abstract

Objective : To evaluate the safety, feasibility, and outcome following radical excision of thymoma with resection and reconstruction of invaded mediastinal vessels.
Study Design : A retrospective study.
Patients and Methods : Six patients with thymoma invading the superior vena cava (SVC) and/or the brachiocephalic veins (BCVs) were reviewed in this study. All the patients underwent radical excision of the tumor along with invaded mediastinal vessels followed by vessel reconstruction or repair. The clinical presentation, operative details, postoperative course, and follow-up were reviewed and analyzed.
Results : Three patients presented with features suggestive of SVC syndrome. Contrast-enhanced computed tomography of the chest was the primary imaging modality, which detected a tumor with invasion of major mediastinal veins. WHO type B2 was the commonest histologic type, which was seen in 4 cases. Intraoperatively, SVC invasion, SVC and BCV invasion, and BCV invasions alone were seen in 1, 2, and 3 cases, respectively. The vessels were reconstructed with a prosthetic graft in 3 patients, and autologous pericardial tube graft was used in 1 patient. Two patients had primary repair of the wall of the involved vessel. Postoperative course was complicated by ventilator support requirement in 2, graft thrombosis in 2, acute renal failure in 1 and pneumonia in 1 patient. All patients are alive at the end of follow-up period ranging between 18 and 24 months.
Conclusion: Thymoma excision with the reconstruction of SVC or BCV is safe and feasible in experienced hands.

Keywords
Invasive thymoma, superior vena cava, vessel reconstruction

 
© Copyright 2010 Indian Journal of Cancer.
Alternative site location: http://www.indianjcancer.com/

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