search
for
 About Bioline  All Journals  Testimonials  Membership  News


Indian Journal of Cancer
Medknow Publications on behalf of Indian Cancer Society
ISSN: 0019-509X
EISSN: 0019-509X
Vol. 48, No. 1, 2011, pp. 94-98
Bioline Code: cn11015
Full paper language: English
Document type: Review Article
Document available free of charge

Indian Journal of Cancer, Vol. 48, No. 1, 2011, pp. 94-98

 en Helicobacter pylori check for this species in other resources infection in relation to gastric cancer progression
Venkateshwari, A.; Krishnaveni, D.; Venugopal, S.; Shashikumar, P.; Vidyasagar, A. & Jyothy, A.

Abstract

Gastric cancer is a major cause of cancer death worldwide, especially in developing countries. The incidence of gastric cancer varies from country to country, probably as a result of genetic, epigenetic, and environmental factors. H. pylori infection is considered as a major risk factor in the development of gastric cancer. However, the scenario varies in Asian countries, exhibiting a higher rate of H. pylori infection and low incidence of gastric cancer, which could be attributed to strain-specific virulence factors and host genetic makeup. In this review, we discuss the various virulence factors expressed by this bacterium and their interaction with the host factors, to influence pathogenesis.

Keywords
Cytotoxicity associated pathogenicity Island, gastric cancer, H. pylori, ice A gene, vacuolating cytotoxin

 
© Copyright 2011 Indian Journal of Cancer.
Alternative site location: http://www.indianjcancer.com/

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2024, Site last up-dated on 01-Sep-2022.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Google Cloud Platform, GCP, Brazil