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Indian Journal of Cancer
Medknow Publications on behalf of Indian Cancer Society
ISSN: 0019-509X
EISSN: 0019-509X
Vol. 48, No. 4, 2011, pp. 507-512
Bioline Code: cn11134
Full paper language: English
Document type: Review Article
Document available free of charge

Indian Journal of Cancer, Vol. 48, No. 4, 2011, pp. 507-512

 en Epigenetic changes in tumor microenvironment
Dey, P


The drama of cancer is not the solo performance of the malignant cells. Microenvironment of the tumor has significant contribution in carcinogenesis. Recent evidences show distinct gene promoter methylation in stromal cells of various malignant and pre-malignant tumors. These changes probably create unique tumor microenvironment, which is responsible for initiation, proliferation, invasion, and metastasis of tumor cells. In this mini review the role of epigenetic changes of tumor microenvironment in carcinogenesis has been discussed.

Carcinogenesis, epigenetics, microenvironment, stroma, tumor

© Copyright 2011 - Indian Journal of Cancer
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