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Journal of Cancer Research and Therapeutics
Medknow Publications on behalf of the Association of Radiation Oncologists of India (AROI)
ISSN: 0973-1482
EISSN: 1998-4138
Vol. 5, No. 4, 2009, pp. 324-327
Bioline Code: cr09079
Full paper language: English
Document type: Case Report
Document available free of charge

Journal of Cancer Research and Therapeutics, Vol. 5, No. 4, 2009, pp. 324-327

 en An unusual case of clear cell meningioma
Deb, Prabal & Datta, Subramanya G.S.


Clear-cell meningioma (CCM) is an uncommon, aggressive variant of meningioma, usually affecting younger females and having predilection for infratentorial locations. We present a rare case of recurrent supratentorial CCM in a 58-year-old male. Ten years back, he had an intra-axial tumor in the left occipital lobe, which was managed by surgical excision and radiotherapy. Currently, the patient presented with sudden severe headache along with speech and vision disturbances. Neuroimaging revealed an extra-axial parietooccipital tumor, with intratumoural bleed. Histopathology of both tumors showed features of CCM, immunopositive for epithelial membrane antigen (EMA) and vimentin. This case illustrates multiple unusual features of a rare variant of meningioma in the form of affection of an adult age group, supratentorial location, recurrence, and intratumoral bleed. It also highlights the importance of incorporating immunohistochemistry in the diagnostic workup, to exclude CCM mimics, each having distinctive biological behavior, and prognostic outcome, and warranting different therapeutic protocols.

Adult, clear-cell meningioma, intraparenchymal, intratumoral hemorrhage, supratentorial

© Copyright 2009 Journal of Cancer Research and Therapeutics.
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