Study - Mucosal and peri-orificial involvement in Post-Kala-Azar dermal leishmaniasis

BACKGROUND AND AIMS: Lesions of post-kala-azar dermal leishmaniasis (PKDL) usually affect the skin. Uncommonly, the involvement of oral and genital mucosae has been reported.
METHODS: Twenty five patients clinically diagnosed as post-kala-azar dermal leishmaniasis were studied for periorificial and mucosal lesions. Clinical examination, skin smears and biopsy were done for the patients with periorificial or mucosal lesions.
RESULTS: Out of 25 patients of PKDL, seven patients had lesions on the oral and/or genital mucosa. Three cases had oral lesions; two had only genital lesions and three patients had both sites involved. All the patients were having skin lesions elsewhere too either as nodules and/or plaque or macules.
Conclusion: While examining a case of PKDL, mucosal involvement must also be examined carefully.

Keywords
Post-kala-azar dermal leishmaniasis, oral mucosa, genital lesions, peri-orificial lesions