About Bioline  All Journals  Testimonials  Membership  News

Indian Journal of Dermatology, Venereology and Leprology
Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)
ISSN: 0378-6323
EISSN: 0378-6323
Vol. 71, No. 4, 2005, pp. 250-253
Bioline Code: dv05084
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Dermatology, Venereology and Leprology, Vol. 71, No. 4, 2005, pp. 250-253

 en Studies - Post-kala-azar dermal leishmaniasis: A histopathological study
Rathi SanjayK, Pandhi RK, Chopra P, Khanna N


BACKGROUND : Post-kala-azar dermal leishmaniasis follows an attack of visceral leishmaniasis and is caused by the same organism, i.e. Leishmania donovani check for this species in other resources .
METHODS: In the present study, biopsy specimens from hypopigmented macules, nodules or plaques of 25 patients clinically diagnosed as PKDL were evaluated for epidermal and dermal changes and for the presence or absence of Leishmania donovani bodies (LDBs).
RESULTS : The hypopigmented macules showed a patchy perivascular and periappendageal infiltrate with no demonstrable LDBs in any of the biopsies. In the nodular and plaque lesions, the infiltrate was diffuse, beneath an atrophic epidermis (74%) and follicular plugging (95.6%) was seen in most biopsies. The infiltrate consisted of lymphocytes, histiocytes and plasma cells in decreasing order of presence. LDBs could be demonstrated in only 10 (43.5%) biopsy specimens from nodular and plaque lesions and were never numerous.
CONCLUSIONS: Histopathological features of PKDL are elucidated and discussed.

Post kala-azar dermal leishmaniasis, Hypopigmented macules, Nodules, Plaques, Histopathology

© Copyright 2005 Indian Journal of Dermatology, Venereology and Leprology.
Alternative site location:

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2024, Site last up-dated on 01-Sep-2022.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Google Cloud Platform, GCP, Brazil