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Indian Journal of Dermatology, Venereology and Leprology
Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)
ISSN: 0378-6323 EISSN: 0378-6323
Vol. 71, No. 5, 2005, pp. 342-344
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Bioline Code: dv05112
Full paper language: English
Document type: Research Article
Document available free of charge
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Indian Journal of Dermatology, Venereology and Leprology, Vol. 71, No. 5, 2005, pp. 342-344
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Case Report - Rosai-dorfman syndrome
Riyaz Najeeba, Khader Anza, Sarita S
Abstract
Rosai-Dorfman syndrome is characterized by sinus histiocytosis with massive lymphadenopathy. A 25-year-old woman presented with multiple erythematous and yellowish papules on the forehead, cheeks, chin and thigh. She had massive generalized, firm, non-tender and non-matted lymphadenopathy and mild hepatomegaly. Her hemogram was normal. A skin biopsy showed collections of histiocytes with emperipolesis and plenty of plasma cells. A lymph node biopsy showed partial loss of architecture, dilated sinuses filled with histiocytes, which showed lymphocytophagocytosis, anisonucleosis and a clear cytoplasm. She was referred to an oncologist for further management.
Keywords
Sinus histiocytosis, Massive lymphadenopathy, Rosai-Dorfman syndrome
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© Copyright 2005 Indian Journal of Dermatology, Venereology and Leprology. Alternative site location: http://www.ijdvl.com
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