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Indian Journal of Dermatology, Venereology and Leprology
Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)
ISSN: 0378-6323
EISSN: 0378-6323
Vol. 73, No. 4, 2007, pp. 253-256
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Bioline Code: dv07091
Full paper language: English
Document type: Research Article
Document available free of charge
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Indian Journal of Dermatology, Venereology and Leprology, Vol. 73, No. 4, 2007, pp. 253-256
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Case Report - Type I lepra reaction presenting as immune reconstitution inflammatory syndrome
Kharkar, Vidya; Bhor, Urmila H.; Mahajan, Sunanda & Khopkar, Uday
Abstract
Immune reconstitution inflammatory syndrome (IRIS) is an unusual inflammatory reaction due to infectious and non-infectious causes occurring in human Immunodeficiency virus (HIV)-infected patients. IRIS occurs after the initiation of antiretroviral therapy. There are no reports of type I lepra reaction due to IRIS in published literature from India. We report two cases of HIV-infected males who presented with borderline tuberculoid leprosy in type 1 reaction after the initiation of highly active antiretroviral treatment (HAART). Case 1 presented with multiple, tender, erythematous and hypoesthetic plaques on the trunk and extremities after 3 months of antiretroviral therapy. In case 2, type I lepra reaction was observed 2 months after the initiation of HAART.
Keywords
Borderline tuberculoid leprosy, Highly active antiretroviral treatment, Immune reconstitution inflammatory syndrome, Reversal reaction, Type I lepra reaction
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© Copyright 2007 Indian Journal of Dermatology, Venereology and Leprology.
Alternative site location: http://www.ijdvl.com
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