Several serovars of
Salmonella
infect and kill the nematode
C. elegans. However, here we report that
Salmonella typhi
Ty2, a representative strain of this human pathogen, readily infects the intestinal lining of
C. elegans without significantly affecting its viability. Our observation suggests extending the use of the
C. elegans model system for the study of host parasite relationships, to address problems concerning the biology of
S. typhi.
