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Electronic Journal of Biotechnology
Universidad Católica de Valparaíso
ISSN: 0717-3458
Vol. 18, No. 5, 2015, pp. 347-354
Bioline Code: ej15058
Full paper language: English
Document type: Research Article
Document available free of charge

Electronic Journal of Biotechnology, Vol. 18, No. 5, 2015, pp. 347-354

 en Soft computing model on genetic diversity and pathotype differentiation of pathogens: A novel approach
Gürüler, Hüseyin; Peker, Musa & Baysal, Ömür


Background: Identifying and validating biomarkers' scores of polymorphic bands are important for studies related to the molecular diversity of pathogens. Although these validations provide more relevant results, the experiments are very complex and time-consuming. Besides rapid identification of plant pathogens causing disease, assessing genetic diversity and pathotype formation using automated soft computing methods are advantageous in terms of following genetic variation of pathogens on plants. In the present study, artificial neural network (ANN) as a soft computing method was applied to classify plant pathogen types and fungicide susceptibilities using the presenceabsence of certain sequence markers as predictive features.
Results: A plant pathogen, causing downy mildewdisease on cucurbitswas considered as amodelmicroorganism. Significant accuracy was achieved with particle swarm optimization (PSO) trained ANNs.
Conclusions: This pioneer study for estimation of pathogen properties using molecularmarkers demonstrates that neural networks achieve good performance for the proposed application.

Computational biology; Genetic diversity; Molecular markers; Plant pathogens; Predictive information; Soft computing

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