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European Journal of General Medicine
Medical Investigations Society
ISSN: 1304-3897
Vol. 3, No. 4, 2006, pp. 184-185
Bioline Code: gm06039
Full paper language: English
Document type: Research Article
Document available free of charge

European Journal of General Medicine, Vol. 3, No. 4, 2006, pp. 184-185

Cefle, Ayse & Yazici, Ayten


Sustained-release bupropion is commonly used for the symptomatic relief of depressive disorders and as an adjuvant in smoking cessation therapy. The frequency of adverse reactions with bupropion has been estimated to be more than 1%. Hypersensitivity reactions to bupropion are fairly common and include rare cases of serum sickness-like reaction. Here we report a case of bupropion hydrochloride induced serum sickness-like reaction. Complete resolution of symptoms was achieved on discontinuing bupropion and instituting therapy with glucocorticoid and a non-steroidal antiinflammatory drug.We report this case to notify clinicians of potential serious multisystem complications that can occur with sustained-release bupropion therapy.

Bupropion; adverse reactions; arthritis; serum sickness-like reactions

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