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European Journal of General Medicine
Medical Investigations Society
ISSN: 1304-3897
Vol. 4, No. 1, 2007, pp. 50-53
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Bioline Code: gm07012
Full paper language: English
Document type: Research Article
Document available free of charge
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European Journal of General Medicine, Vol. 4, No. 1, 2007, pp. 50-53
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LICHENOID DRUG ERUPTION ASSOCIATED WITH IMATINIB MESYLATE: TWO CASES
Ilhami, Kiki; Mustafa, Atasoy; Nesrin, Gursan; Mehmet, Gundogdu; Fuat, Erdem & Sevki, Ozdemir
Abstract
Imatinib mesylate (STI571) is a new therapeutic agent which inhibits the tyrosine kinase of the BCR-ABL, c-kit and platelet derived growth factor oncogenes. It is used for the treatment of chronic myelogenous leukemia, Philadelphia chromosome positive acute lymphoblastic leukemia and gastrointestinal stromal tumors. Although, cutaneous side effects of this drug is common, lichenoid eruption is exceptional. We report two cases of disseminated lichenoid cutaneous reaction, which developed in two patients with chronic myelogenous leukemia treated with imatinib mesylate.
Keywords
Imatinib mesylate, chronic myelogenous leukemia, lichenoid eruption
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