Assessment Of Antioxidants And Nutritional Status Of Pulmonary Tuberculosis Patients In Nigeria|
Moses, Akiibinu O; Emmanuel, Ogunyemi O; Ganiyu, Arinola O; Fidelis, Adenaike A & Dickson, Adegoke O
The aim of this study was to assess the nutritional and antioxidant status of pulmonary tuberculosis patients in Nigeria
Levels of total protein (TP), albumin (ALB.), triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDLC), low density lipoprotein cholesterol (LDLC), and total antioxidants (TAS) were determined in thirty-one Nigerian pulmonary tuberculosis patients and thirty-four controls using Spectrophotometric methods
The mean levels of TP (7.13±1.06g/dl), ALB (3.27±0.7g/dl), TC (100.7±23.6mg/dl), HDLC (28.6±7.2mg/dl), LDLC (65.5±15.1mg/dl) and TG (61.6±16.2mg/dl) were significantly lower while the level of globulin (3.9±0.84g/dl) was significantly higher in pulmonary tuberculosis patients when compared with controls (TP= 7.6±0.7g/dl; ALB= 4.2±0.48g/dl; TC = 163.2±40.1mg/dl; HDLC = 41.4±5.4mg/dl; LDLC = 107.8±27.5mg/dl; TG= 101.5±29mg/dl; globulin = 3.4±0.6g/dl respectively).
Level of TAS (0.83±0.34mmol/l) was significantly lower when compared with controls (TAS= 1.65±0.26mmol/l). The significantly lower level of antioxidants observed in this study might be due to heavy load of free radicals released by the bacterial invaded macrophages.
The nutritional derangement and lower antioxidant status could call for prompt nutritional intervention in the management of pulmonary tuberculosis patients.
Pulmonary tuberculosis, antioxidants, nutritional status, Nigeria