European Journal of General Medicine
Medical Investigations Society
Vol. 5, No. 4, 2008, pp. 212-215
Bioline Code: gm08042
Full paper language: English
Document type: Research Article
Document available free of charge
European Journal of General Medicine, Vol. 5, No. 4, 2008, pp. 212-215
© Copyright 2008 - Medical Investigations Society
How To Manage Intrauterine Growth Restriction Associated With Severe Preeclampsia At 28-34 Weeks Of Gestation?|
Gezginç, Kazım; Acar, Ali; Peru, Harun; Karataylı, Rengin; Çelik, Çetin & Çapar, Metin
To propose optimal management of intrauterine growth restriction (IUGR) cases associated with severe preeclampsia at 28-34 weeks of gestation.
Two hundred pregnant women with severe preeclampsia associated with growth restricted fetuses were followed with doppler velocimetry of umbilical artery between 28-34 weeks of pregnancy. Patients were grouped according to indications for termination of pregnancy, first group consisted of severely affected doppler velocity waveforms (n:100) and the second group consisted of those whose cardiotocography and biophysic profile were unfavorable (n:100). Groups were compared according to perinatal outcomes (cesarean rates, gestational age at delivery, birth weight, Apgar scores and demand for intubation and perinatal deaths).
The diagnosis to delivery interval is significantly higher in the second group (p<0.05), whereas there was no significant difference between groups regarding gestational age at delivery and parity (p>0.05). Apgar scores were lower in the first group (p<0.05), and there was increased demand for intubation. Perinatal deaths were also lower in the second group (p<0.05). Cesarean rate was significantly lower compared with first group (p<0.05).
Assessment of doppler velocimetry alone may not be enough at decision for termination of pregnancy, biophysic profile and cardiotocography should be added to confirm exact time for delivery of a premature fetus and to improve perinatal outcomes.
Severe Preeclampsia, Intrauterine Growth Restriction, Doppler Velocimetry, Biophysic Profile, Perinatal Outcomes
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