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European Journal of General Medicine
Medical Investigations Society
ISSN: 1304-3897
Vol. 6, No. 2, 2009, pp. 99-102
Bioline Code: gm09022
Full paper language: English
Document type: Research Article
Document available free of charge

European Journal of General Medicine, Vol. 6, No. 2, 2009, pp. 99-102

 en Association of Mean Platelet Volume With The Degree of Retinopathy in Patients with Diabetes Mellitus
Ateş, Orhan; Kiki, İlhami; Bilen, Habip; Keleş, Mustafa; Koçer, İbrahim; Kulaçoğlu, Destan Nil & Baykal, Orhan


Aim: We investigated the association of mean platelet volume (MPV) with the degree of retinopathy in patients with diabetes mellitus (DM).
Methods: Ninety patients with diabetic retinopathy (DRP) and 30 healthy individuals were included in the study. Diabetic patients included 30 background, 30 non-proliferative and 30 proliferative diabetic retinopathy cases. Complete blood count, intra- and intergroup comparisons of MPV values were performed.
Results: Mean values for MPV in patients with background, nonproliferative and proliferative DRP were 7.76±0.72 fL, 7.94±0.61 fL and 8.18±0.89 fL, respectively. MPV values of patients with background DRP was not significantly different from that of the control group and patients with non-proliferative and proliferative DRP as well. However, MPV values of patients with proliferative DRP were significantly higher than the values of control group (p< 0.05). A significant correlation was found between the degree of retinopathy and mean values of MPV in diabetic patients (r= 0.214, p< 0.05). Conclusions: We found an association between the degree of retinopathy and mean values of MPV. This finding suggests a role for platelets in the pathogenesis of vascular complications and that mean platelet volume would be useful in monitoring the disease progression.

Diabetes mellitus, retinopathy, mean platelet volume

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