Pyoderma Gangrenosum Presenting with Pulmonary Cavitary Lesions

Neutrophilic dermatoses like pyoderma gangrenosum (PG) are characterized by sterile, neutrophilic, cutaneous infiltrates. Extracutenous neutrophilic infiltrations may also be seen, but pulmonary involvement is very rare and usually characterized by patchy infiltrates or interstitial pneumonitis. In this case, a PG case who had cutenous lesions and large cavitary lung nodules, is reported. He was a 49 years old male patient whose thorax computed tomography revealed multiple pulmonary nodules with central necrosis. In his transbronchial and bronchial biopsies, nonspecific inflammatory aseptic nodules were detected corresponded to the pathologic findings of skin lesion biopsies. A dramatic response was occured after applying corticosteroid and immunesupressive treatment. In conclusion, cavitary pulmonary nodules of our case were thought to be due to pulmonary involvement of PG.