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European Journal of General Medicine
Medical Investigations Society
ISSN: 1304-3897
Vol. 6, No. 3, 2009, pp. 150-153
Bioline Code: gm09033
Full paper language: English
Document type: Research Article
Document available free of charge

European Journal of General Medicine, Vol. 6, No. 3, 2009, pp. 150-153

 en Clinico-pathological assessment of hysterectomies in Zaria
Samaila Modupeola, O. A.; Adesiyun, A. G.; Agunbiade, O. A. & Mohammed-Duro, A.


Aim: To assess and compare accuracy of the clinical indications and histopathological diagnoses from hysterectomy specimens in Zaria.

Methods: All hysterectomy specimens received in the department of Pathology, Ahmadu Bello University Teaching Hospital, Zaria from January 1995 to December 2005 were analyzed. The speci-mens were fixed in formalin, processed in paraffin wax and his-tology slides stained with haematoxylin and eosin were studied. Frequency of clinical indications were compiled and compared with histopathological diagnoses.

Results: 317 hysterectomies were analyzed. Of these 288 (90.9%) were associated with salpingo-oophrectomies. Median age of pa-tients′ was 45 years and mean age was 44.6 years. Parity of the women ranged from 0-11 with an average of 4.

The clinical indications comprised non-neoplastic- 47 (14.8%) and neoplastic-226 (71.3%) causes. The commonest benign neoplastic indication was uterine fibroid 196 (61.8%). Malignant neoplastic in-dication included cervical cancer 12 (3.8%) and endometrial cancer 6 (1.9%). Cervical intraepithelial neoplasia (CIN), a preneoplastic lesion accounted for 44 (13.9%). Histopathological diagnosis of leiomyoma was made in 218 (68.8%), cervical cancer -20 (6.3%) and CIN- 49 (15.5%). Incidental pathologies seen included chronic cervi-citis -24, adenomyosis- 13 and cystadenoma - 8. Clinical indications in 14 (4.4%) patients were at variance with histological diagnosis.

Conclusion: The clinical indication for hysterectomy and histo-pathological outcome are comparable in over 90% of cases. The commonest indication and histological finding in our setting is leiomyoma.

Hysterectomy, Indication, Pathology, Leiomyoma

© Copyright 2009 European Journal of General Medicine.
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