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European Journal of General Medicine
Medical Investigations Society
ISSN: 1304-3897
Vol. 6, No. 3, 2009, pp. 166-169
Bioline Code: gm09036
Full paper language: English
Document type: Research Article
Document available free of charge

European Journal of General Medicine, Vol. 6, No. 3, 2009, pp. 166-169

 en Serum uric acid levels in patients with relapsing-remitting multiple sclerosis
Altınkaynak, Konca; Varoğlu, Asuman Orhan; Aksoy, Hülya; Deniz, Orhan & Aksoy, Asude

Abstract

Aim: Multiple sclerosis (MS) is an inflammatory demyelinating dis-ease with unknown origin. Several studies suggest lower levels of serum uric acid (UA), an endogenous antioxidant, in MS patients. Methods: In this study, we aimed to investigate serum UA levels in relapsing-remitting (RR) MS. In addition we compared serum UA levels by means of clinical activity, expanded disability status scale (EDSS) and disease duration.

Results: In the present study, mean serum UA levels were lower in RRMS and relapse patients with MS than in the other neuro-logical diseases (OND) group, but the difference did not reach significance level. UA levels did not correlate with clinical activity, EDSS score and disease duration either in relapse or remitting or both of them.

Conclusion: In conclusion, this study suggests serum uric acid lev-els may affect neither pathogenesis of MS nor activity of disease. Further studies are needed to clarify the role of uric acid in MS patients.

Keywords
Uric Acid, Activity of Multiple Sclerosis, Endogenous Antioxidant, Pathogenesis

 
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