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European Journal of General Medicine
Medical Investigations Society
ISSN: 1304-3897
Vol. 7, No. 3, 2010, pp. 245-249
Bioline Code: gm10060
Full paper language: English
Document type: Research Article
Document available free of charge

European Journal of General Medicine, Vol. 7, No. 3, 2010, pp. 245-249

 en Carotid Intima-Media Thickness Can Predict Coronary Atherosclerosis in Diabetic Elderly Patients
Amer, Motassem S.; Maher, Mohsen M; Omar, Omar H; Reda, Randa A.; Elawam, Amal E. & Sweed, Hala S


Aim: To evaluate the relationship between coronary risk and carotid vessels as revealed by duplex study in diabetic elderly patients.
Method: Case control study was designed. Participants were recruited from Geriatric department Ain Shams University Hospital, Cairo-Egypt. The cases were subdivided into two groups (group 1: diabetic with coronary artery diseases (CAD), group 2: diabetic without CAD). The diabetic group (cases) included 60 patients (25 males and 35 females). The control group included 30 elderly subjects matched for age and sex. All groups were subjected to: comprehensive geriatric assessment, laboratory measurements including: fasting blood sugar, lipid profile, lipoprotein (a), and carotid duplex for measurement of the intima-media thickness and the degree of stenosis.
Result: On analysis of the collected data, diabetic patients did have atherosclerosis in the carotid arteries more than the non diabetic subjects, and among the diabetic patients group, it was revealed that those who had CAD, had their carotid arteries more atherosclerotic than the others without CAD. Multinomial logistic regression done showed significant independent association between the presence of thickened carotid intima-media and coronary artery disease among diabetic patients (p=0.042, OR 1.71(0.52-5.6)
Conclusion: Thickened carotid intima-media can predict risk to have coronary artery disease among elderly diabetic patients.

Carotid intima-media thickness, coronary atherosclerosis, diabetes

© Copyright 2010 European Journal of General Medicine.
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