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European Journal of General Medicine
Medical Investigations Society
ISSN: 1304-3897
Vol. 7, No. 3, 2010, pp. 245-249
Bioline Code: gm10060
Full paper language: English
Document type: Research Article
Document available free of charge

European Journal of General Medicine, Vol. 7, No. 3, 2010, pp. 245-249

 tr Karotis İntima Media Kalınlığı Yaşlı Diyabetik Hastalarda Koroner Atherosklerozu Öngörebilir
Amer, Motassem S.; Maher, Mohsen M; Omar, Omar H; Reda, Randa A.; Elawam, Amal E. & Sweed, Hala S


Amaç: Yaşlı diyabetik hastalarda doppler ultrason ile değerlendirilen karotid arterler ile koroner risk arasındaki ilişkilerin değerlendirilmesi.
Metod: Çalışma vaka-kontrol şeklinde dizayn edildi. Katılımcılar Ain Shams Universitesi Kahire, Mısır Hastanesinden çalışmaya alındılar. Vakalar iki alt gruba ayrıldılar (Grup 1: Koroner arter hastalığı (KAH) olan diyabetikler, Grup 2: KAH olmayan diyabetikler). Diyabetik grupta 60 hasta mevcuttu (25 erkek, 35 kadın). Kontrol grubu olarak yaş ve cinsiyet açısından eş, 30 yaşlı kişi çalışmaya dahil edildi. Tüm gruplarda kapsamlı geriatrik değerlendirme, açlık kan şekeri, lipid profili, lipoprotein a' yıda içeren laboratuvar incelemeleri yapıldı ve carotis doppler ultrasonu ile intima media kalınlığı ve stenoz derecesi değerlendirildi.
Bulgular: Toplanmış verilerin analizinde diyabetik hastalarde diyabetik olmayanlara göre daha atherosklerotik olduğu, Diyabetik grupta KAH olan grupta KAH olmayanlara göre karotis arterlerinin daha aterosklerotik olduğu gözlemlendi. Multinominal logistic regresyon analizinde diyabetik hastalarda karotid arter intima media kalınlığı ile koroner arter hastalığı arasında bağımsız bir ilişki olduğu tespit edildi (p=0.042, OR 1.71 (0.52-5.6)).
Sonuç: Kalınlaşmış carotis intima media yaşlı diabetik hastalarda KAH'a sahip olma riskini öngörebilmektedir.


Karotis intima media kalınlığı, koroner ateroskleroz, diyabet

 
 en Carotid Intima-Media Thickness Can Predict Coronary Atherosclerosis in Diabetic Elderly Patients
Amer, Motassem S.; Maher, Mohsen M; Omar, Omar H; Reda, Randa A.; Elawam, Amal E. & Sweed, Hala S

Abstract

Aim: To evaluate the relationship between coronary risk and carotid vessels as revealed by duplex study in diabetic elderly patients.
Method: Case control study was designed. Participants were recruited from Geriatric department Ain Shams University Hospital, Cairo-Egypt. The cases were subdivided into two groups (group 1: diabetic with coronary artery diseases (CAD), group 2: diabetic without CAD). The diabetic group (cases) included 60 patients (25 males and 35 females). The control group included 30 elderly subjects matched for age and sex. All groups were subjected to: comprehensive geriatric assessment, laboratory measurements including: fasting blood sugar, lipid profile, lipoprotein (a), and carotid duplex for measurement of the intima-media thickness and the degree of stenosis.
Result: On analysis of the collected data, diabetic patients did have atherosclerosis in the carotid arteries more than the non diabetic subjects, and among the diabetic patients group, it was revealed that those who had CAD, had their carotid arteries more atherosclerotic than the others without CAD. Multinomial logistic regression done showed significant independent association between the presence of thickened carotid intima-media and coronary artery disease among diabetic patients (p=0.042, OR 1.71(0.52-5.6)
Conclusion: Thickened carotid intima-media can predict risk to have coronary artery disease among elderly diabetic patients.

Keywords
Carotid intima-media thickness, coronary atherosclerosis, diabetes

 
© Copyright 2010 European Journal of General Medicine.
Alternative site location: http://www.ejgm.org

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