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Indian Journal of Human Genetics
Medknow Publications on behalf of Indian Society of Human Genetics
ISSN: 0971-6866
EISSN: 0971-6866
Vol. 11, No. 3, 2005, pp. 145-148
Bioline Code: hg05028
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Human Genetics, Vol. 11, No. 3, 2005, pp. 145-148

 en Red cell enzyme and serum protein polymorphisms (ACP1, PGM1, GLO1, ESD, HP, PI) in Turkish population
Donbak L, Csete C, Salacin S, Varga T


Background: The allele frequencies in human populations are used in different areas such as population genetics, forensic genetics and anthropological studies. Various different populations have been investigated their allele frequency distributions of polymorphic traits.
Aims and Objectives: The allele frequency distributions of four red cell enzyme (ACP1, PGM1, GLO1, ESD) and two serum protein systems (HP, PI subtypes) were analyzed in Turkish population from Adana area, Turkey, in order to enlarge our knowledge on the genetic composition of Turkish population.
Material and Methods: Venous blood samples taken from 200 unrelated Turkish individuals were transported to the Forensic Serology Laboratory of Albert Szent-Gy φrgyi Medical University (Szeged/Hungary) for phenotyping. The phenotypes of ACP1, PGM1, GLO1, ESD, and HP systems were determined by means of starch gel electrophoresis, while PI subtypes were obtained by polyacrylamide gel isoelectric focusing method. The allele frequencies were calculated by gene counting.
Results: The calculated frequencies of the alleles are as follows: ACP1*A = 0.250 ± 0.021, ACP1*B = 0.693 ± 0.023, ACP1*C = 0.057 ± 0.011; PGM1*1 = 0.710 ± 0.022, PGM1*2 = 0.288 ± 0.022, PGM1*6 = 0.002 ± 0.002; GLO1*1 = 0.373 ± 0.024, GLO1*2 = 0.627 ± 0.024; ESD*1 = 0.805 ± 0.019, ESD*2 = 0.195 ± 0.019; HP*1 = 0.265 ± 0.022, HP*2 = 0.735 ± 0.022; PI*M1 = 0.887 ± 0.015, PI*M2 = 0.010 ± 0.004, PI*M3 = 0.095 ± 0.014, PI*S = 0.008 ± 0.004.
Conclusions: The comparison of the data with those of Asian and European populations showed that the allele frequencies of ACP1, ESD and HP are similar or close to those of Asian populations, whereas those of PGM1 and PI come close to European populations. The allele frequency of GLO1 system is inbetween those of Asians and Europeans

Erythrocyte enzymes, Serum proteins, Polymorphisms, Population genetics, Turkish population

© Copyright 2005 Indian Journal of Human Genetics.
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