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Indian Journal of Human Genetics
Medknow Publications on behalf of Indian Society of Human Genetics
ISSN: 0971-6866
EISSN: 0971-6866
Vol. 12, No. 2, 2006, pp. 76-81
Bioline Code: hg06013
Full paper language: English
Document type: Research Article
Document available free of charge

Indian Journal of Human Genetics, Vol. 12, No. 2, 2006, pp. 76-81

 en Original Communication - Fluctuating asymmetry in dermatoglyphics of carcinoma of breast
Natekar PrashantE, DeSouza FatimaM


BACKGROUND: More has been written about the epidemiology of breast cancer than any other form of cancer affecting mankind. The specific breast cancer predisposing genes are BRCA1, BRCA2 and p53. BRCA2, the second breast cancer susceptibility gene, was mapped to chromosome 13q12-q13.The human p53 gene, located on the short arm of chromosome 17, is known to be a tumor suppressor gene that can be inactivated by point mutations.
AIMS: To determine the fluctuating asymmetry and to predict the occurrence of carcinoma of breast in females.
MATERIALS AND METHODS: Rolled finger and palmar prints of 100 female patients of carcinoma of breast were compared with 100 controls. Fluctuating asymmetry measures derived from quantitative parameters (finger ridge counts, a-b ridge counts and palmar angles) were analyzed.
RESULTS: Fluctuation asymmetry measures were significantly higher in female patients of carcinoma of breast for the thumb (FA = 2.01), subtotal ridge count (FA = 2.10) and for palmar atd angle (FA = 2.01).
CONCLUSION: These findings suggest that digital dermatoglyphics may have a future role in identifying women at increased risk for breast cancer.

Breast cancer, dermatoglyphics, fingerprints, fluctuating asymmetry, palmar prints

© Copyright 2006 Indian Journal of Human Genetics.
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