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Indian Journal of Human Genetics
Medknow Publications on behalf of Indian Society of Human Genetics
ISSN: 0971-6866
EISSN: 0971-6866
Vol. 15, No. 3, 2009, pp. 137-139
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Bioline Code: hg09029
Full paper language: English
Document type: Research Article
Document available free of charge
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Indian Journal of Human Genetics, Vol. 15, No. 3, 2009, pp. 137-139
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A new recurring chromosome 13 abnormality in two older patients with de novo acute myeloid leukemia: An Indian experience
Trivedi, P J.; Patel, P S.; Brahmbhatt, M M.; Patel, B P.; Gajjar, S B.; Dalal, E N.; Shukla, S N.; Shah, P M. & Bakshi, S R.
Abstract
We report here two cases of trisomy 13 in acute myeloid leukemia M1 subtype. short-term unstimulated bone marrow and peripheral blood lymphocyte culture showed 47, XY, +13 in all metaphase plates and trisomy 13 was confirmed with whole chromosome paint probes. Trisomy 13 in AML-M1 is a rare numerical abnormality. This is the first Indian report of sole trisomy 13 in AML-M1. Here, we present two cases of elder male patients, which may constitute a distinct subtype.
Keywords
Acute myeloid leukemia-M1, recurrent, sole abnormality, trisomy 13
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© Copyright 2009 Indian Journal of Human Genetics.
Alternative site location: http://www.ijhg.com/
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