Indian Journal of Human Genetics
Medknow Publications on behalf of Indian Society of Human Genetics
Vol. 17, No. 2, 2011, pp. 82-84
Bioline Code: hg11019
Full paper language: English
Document type: Research Article
Document available free of charge
Indian Journal of Human Genetics, Vol. 17, No. 2, 2011, pp. 82-84
© Copyright 2011 Indian Journal of Human Genetics.
Chromosomal abnormalities as a cause of recurrent abortions in Egypt|
Mogib El-Dahtory, Faeza Abdel.
Background: In 4%-8% of couples with recurrent abortion, at least one of the partners has chromosomal abnormality. Most spontaneous miscarriages which happen in the first and second trimesters are caused by chromosomal abnormalities. These chromosomal abnormalities may be either numerical or structural.
Material and Methods : Cytogenetic study was done for 73 Egyptian couples who presented with recurrent abortion at Genetic Unit of Children Hospital, Mansoura University.
Results : We found that the frequency of chromosomal abnormalities was not significantly different from that reported worldwide. Chromosomal abnormalities were detected in 9 (6.1%) of 73 couples. Seven of chromosomal abnormalities were structural and two of them were numerical.
Conclusion : Our results showed that 6.1% of the couples with recurrent abortion had chromosomal abnormalities, with no other abnormalities. We suggest that it is necessary to perform cytogenetic in vestigation for couples who have recurrent abortion.
Chromosomal abnormalities, cytogenetics, recurrent abortions
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