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The Journal of Health, Population and Nutrition
icddr,b
ISSN: 1606-0997 EISSN: 1606-0997
Vol. 28, No. 2, 2010, pp. 137-142
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Bioline Code: hn10018
Full paper language: English
Document type: Research Article
Document available free of charge
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The Journal of Health, Population and Nutrition, Vol. 28, No. 2, 2010, pp. 137-142
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Association between Serum Ferritin and Goitre in Iranian School Children
Hashemipour, Mahin; Soheilipour, Fahimeh; Keshteli, Ammar Hassanzadeh; Siavash, Mansour; Amini, Masoud & Kelishadi, Roya
Abstract
Despite long-standing supplementation of iodine in Iran, the prevalence of goitre among general people
remains high in some regions. The study investigated the role of iron status in the aetiology of goitre in
school children in Isfahan, Iran. Two thousand three hundred and thirty-one school children were selected
by multi-stage random sampling. Thyroid size was estimated by inspection and palpation. Urinary iodine
concentration (UIC) and serum ferritin (SF) were measured. Overall, 32.9% of the children had goitre. The
median UIC was 195.5 μg/L. The mean±SD of SF in the goitrous and non-goitrous children was 47.65±42.51
and 44.55±37.07 μg/L respectively (p=0.52). The prevalence of iron deficiency in goitrous and non-goitrous
children was 9.6% and 3.1% respectively (p=0.007). Goitre is still prevalent in school children of Isfahan.
However, their median UIC was well in the accepted range. Iron deficiency is associated with goitre in a
small group of goitrous children. The role of goitrogens should also be investigated in this region.
Keywords
Cross-sectional studies; Goitre; Iodine; Iron deficiency; Serum ferritin; Iran
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